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LONDON, UK (GlobalData), 28 August 2013 - The total combined peer group revenue from Contract Research Organizations (CROs) increased by 10.2% year-to-year, from $12.4 billion in 2011 to $13.6 billion in 2012, driven mainly by greater demand for outsourced clinical services as drug makers look to contractors as a strategy to off-set the high cost of bringing new therapies, states research and consulting firm GlobalData.
In all countries, stigma about mental and substance use disorders constrain the use of available resources as do inefficiencies in the distribution of funding and interventions. If the burden of mental and substance use disorders is to be reduced, mental health policy and services research will need to identify more effective ways to provide sustainable mental health services, especially in resource-constrained environments, he concluded.
This study shows that the U.S., unlike most other high-income countries, has had little change in the use of corporal punishment as commonplace, Zolotor said in the UNC news release. Given the weight of evidence that spanking does more harm than good, it is important that parents understand the full range of options for helping to teach their children. A bit of good news is that the decline in the use of harsher forms of punishment is somewhat more impressive.
The EMILIA trial assessed Kadcyla compared to standard therapy for the treatment of patients with HER2-positive metastatic breast cancer who had previously received Herceptin? (trastuzumab) and a taxane. Kadcyla demonstrated a significant improvement in overall survival and in progression-free survival, and fewer patients experienced severe adverse events, compared to standard therapy.
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He agreed with the study authors that, a few standardized screening questions, consistently asked of all patients, could quickly identify those who would benefit from either education or referral to specialized care.
And in an accompanying commentary in the journal, two American doctors cautioned that the drug is expensive, costing $2,124 to $7,380 in New York City for a once-daily, 45-day supply. They recommended that government officials spend more time studying the drug and its cost-effectiveness. Until there's a consensus, they wrote, it would be premature to recommend the drug for this use.
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